Department of Bioinformatics – BiGCaT


The BiGCaT core projects each have their own project page, which can be found here.

There are several tutorials available for these tools and software, which can be found here.

High-throughput data analysis pipelines

  • ArrayAnalysis: Quality Control, pre-processing, normalization and statistics of Affymetrix microarrays. ArrayAnalysis offers user-friendly solutions for gene expression data analysis, from raw data to biological pathways. It contains modules of three types that can be lauched individually or successively as an integrated workflow.

Identifier Mapping

  • BridgeDb: identifier mapping framework for bioinformatics applications.

  • Open PHACTS: Bringing together pharmacological data resources in an integrated, interoperable infrastructure. Open PHACTS started as an IMI-funded project to integrate data sources like ChEMBL, WikiPathways, Uniprot, and DisGenet to support drug discovery by the pharmaceutical industry.

 The Phenotype Data Infrastructure

  • DBNP: An open source application suite to store biological studies. The central module (GSCF) stores the study design, which links out to modules that contain the measurements of specific measurement platforms.

Semantic Web tools using RDF and SPARQL

  • Open PHACTS: drug discovery in industry, academia and for small businesses

  • WikiPathways RDF: SPARQL endpoint of WikiPathways to query pathway data

Structuring and collecting biological processes in WikiPathways

Pathway analysis in PathVisio

  • PathVisio: a tool to edit and analyze biological pathways

  • Facilitating PathVisio use in familiar analytical environments :

  • GoElite: extended pathway and Gene Ontology analysis

Network Analysis with Cytoscape

  • CyTargetLinker: a generic Cytoscape app to build regulatory networks

  • SemScape: Visualizes Semantic Data Landscapes (Google Summer of Code project 2012)